GenePaint™

Innovative solution for automated in situ hybridization (ISH) flourescence in situ hybridization (FISH) and immunohistochemistry (IHC)

Tecan’s GenePaint system, which is based on a new flow-through technology, automates all of the steps required for performing in situ hybridization of tissues on microscope slide formats. One of the key steps in the study of gene expression is the validation of results obtained by in vitro gene expression methods (microarrays, blots, etc.). This validation typically involves the use of appropriate cell or tissue samples and the performance of in situ hybridization (ISH) to confirm the in vitro results. The unique advantage of in situ hybridization over destructive expression techniques such as microarrays is the localization of transcripts in intact cells and tissues, giving a much higher level of information. However, processing of large numbers of cell or tissue samples in these type of procedures is an extremely time consuming and laborious process. GenePaint alleviates this throughput bottleneck.

Advanced features for functional genomic studies

eliminates 80% of the manual steps of conventional ISH, FISH or IHC analysis
extends walk-away time through unattended hybridization protocols
allows the use of any commercial set of reagents for hybridization studies
assures consistent and reproducible results of excellent quality
saves on the amounts of reagents used

The applications described here are not available in the US outside of the research market.

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GenePaint

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