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Infinite® F500 - Applications

The optimal filter based microplate reader for biopharmaceutical, life science and research laboratories

The fast and sensitive Infinite F500 filter-based microplate reader is ideal for a broad range of applications, in particular ratiometric assays and other technologies routinely used within assay development, screening and ADMET laboratories, research institutes and the Life Sciences industry. It is capable of reading 6 to 1536-well microplates, including standard and low-volume plates.


The Infinite F500 microplate reader supports many different applications and assay technologies, such as:

  • TR-FRET-based assays: e.g. HTRF® (Cisbio bioassays, France), LanthaScreen® (Invitrogen).
  • FRET-based assays: e.g. Z`-LYTE® (Invitrogen) to study cellular protein kinases, GeneBLAzer® (Invitrogen) Reporter Gene assays.
  • Glow luminescence: cell-based & reporter gene assays
  • Flash luminescence: e.g. dual color luminescence assays, flash luminescence for Ca2+ detection by photoproteins
  • Fluorescence polarization: e.g. Predictor™ hERG Fluorescence Polarization Assay (Invitrogen), PolarScreen™ Glucocorticoid Receptor Competitor Assay Kit, Red (Invitrogen), PolarScreen™ Glucocorticoid Receptor Competitor Assay Kit, Green (Invitrogen), Transcreener® ADP Assay (BellBrook Labs)
  • Ion channel: calcium studies using certain ion sensitive dyes

The Infinite F500 has been validated by Invitrogen for the following Invitrogen assays:

  • LanthaScreen®
  • Adapta® Universal Kinase Assay
  • Omnia®
  • Z’-LYTE®
  • GeneBLAzer®
  • PolarScreen™
  • Predictor™ hERG Fluorescence Polarization Assay

If you are interested in more details on the applications for the Infinite F500 microplate reader, please take a look at the related literature.

 

LanthaScreen® Certified  

The Infinite F500 has been granted the LanthaScreen® Certified Plus Status by Invitrogen

PolarScreen and Predictor are trademarks of Invitrogen Corporation, Carlsbad, USA.
LanthaScreen, Adapta, GeneBLAzer, Omnia and Z’-LYTE are registered trademarks of Invitrogen Corporation, Carlsbad, USA.

 
 

The Infinite F500 has been successfully validated and certified for HTRF® by CisBio bioassays.

HTRF® is a registered trademark of Cisbio international, France. The fluorescence ratio associated with the HTRF® readout is a correction method developed by Cisbio international and covered by the US patent 5,527,684 and its foreign equivalents, for which Cisbio international has granted a license to Tecan Group Ltd. Its application is strictly limited to the use of HTRF® reagents and technology, excluding any other TR-FRET technologies.

 

 

 

The Infinite F500 has been successfully Transcreener® Far Red FP and Transcreener® FI validated by BellBrook Labs, LLC, USA and meets the requirements for BellBrook Labs’ Instrument Validation Program.

Transcreener® HTS Assay Platform is a patented technology of BellBrook Labs, LLC USA. Transcreener® is a registered trademark of BellBrook Labs, LLC USA.

 
 

The Infinite F500 has passed the DLReady™ validation at Promega and is certified as DLReady™.

DLReady™ is a trademark of Promega Corporation, USA.

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