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Plasma Protein Binding

Add Plasma Protein Binding data to your compounds ADME profile to speed up time to clinic

Automation of the liquid handling for the Thermo Scientific RED Device for Rapid Equilibrium Dialysis allows for high through-put plasma protein binding studies to be carried out.


The RED Device allows for:

  • The determination of free vs. bound drug to plasma proteins.
  • Ease of use – disposable tubes require no presoaking, assembly or specialized equipment
  • Short incubation time – equilibrium can be reached in as few as three hours as a result of the high membrane surface-to-volume ratio
  • Its 96-well format – is ideally suited for automation on the Freedom EVO
  • Flexible – can be used for the desired number of assays (one to 48 assays/plate) without wasting the entire plate
  • Robust – compartmentalized design eliminates potential for crosstalk or leakage
  • Reproducible and accurate – validated for plasma-binding assays
The applications described here are not available in the US outside of the research market.


Scientific instrumentation. Not for use in human clinical or in-vitro diagnostic procedures.