siRNA screening

siRNA screening studies have become a standard experimental approach for target identification and target validation in drug discovery, and siRNAs and miRNAs are even being discussed as potential therapeutical agents. The success of such experiments depends on the robustness of the protocols applied and reproducibility of the experimental procedure.

Tecan offers solutions to automate all steps of siRNA studies.
As researchers will need to follow their own optimized protocols, or those of the specific kit or reagent suppliers, we offer tailored solutions based on the Freedom EVO® liquid handling workstation, in combination with specialized modules and detection devices.

Reproducibility of results is of particular importance to this application, and Tecan’s automated solutions ensure identical conditions and scheduling for each experiment. Benefits include:

• Repeatable timings for cationic liposome-RNA complex formation
• Rapid and low CV plating of cells over assay plates
• Low temperature variations over whole process with integrated robotic incubators, fast media exchanges and experiment readouts

Tecan workstations have a proven track record for automation of siRNA screening, minimizing your process risk and ensuring valuable material is not lost. Published studies using Tecan instruments include:

• Screening for infectious virus entry into mammalian cells
• Protein expression knockdown in human T-cells
• Identification of primary cancers

Are you looking for your own customized solution? Do you want to integrate a specific device? Tecan Integration Group supports you in planning, realization and final installation of a tailor-made solution specific designed for your needs.

Scientific instrumentation. Not for use in human clinical or in-vitro diagnostic procedures.