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Selected category: Freedom EVO

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Expanding the experimental space

Biomanufacturing requires careful separation of the molecule of interest from other cellular products to ensure the quality and stability of the final product. This is even more important for the manufacture of biotherapeutics, as the presence of unwanted molecules in pharmaceutical preparations can affect the efficacy and safety of biologically-derived drugs. FUJIFILM Diosynth Biotechnologies is using automated chromatography condition screening to generate more data in less time, helping to improve the performance of purification processes and accelerate biological drug manufacturing.

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5 ml disposable tips now available for LiHa Arm5 ml disposable tips now available for LiHa Arm

Tecan has further extended the flexibility of the Freedom EVO Liquid Handling (LiHa) Arm with the launch of a 5 ml disposable tip. Previously only available to Tecan customers working with fixed tips, the unrivalled pipetting volume range offered by the LiHa Arm can now be exploited by customers who require the highest levels of sample security.

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Faster processing for biosimilars

The biosimilars market is expanding rapidly as the patents expire for an increasing number of high profile biopharmaceutical agents. The complex nature of biologics requires extensive characterization of the production techniques and in vivo effects of new biosimilars before they can be released onto the market. Coherus Biosciences is using advanced laboratory automation to help screen chromatography conditions as part of its downstream purification processes for new biosimilars.

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Time saved in diagnostic vitamin B testing

Mass spectrometry is rapidly becoming the method of choice for quantitative analysis of micronutrients such as vitamins B1, B6, B12 and D, as well as for steroids, hormones and many other drugs. For clinical laboratories, the bottleneck of MS-based techniques is not the analysis, but the pre-processing of the samples to remove proteins and other biological molecules that could interfere with the results.

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Synthetic biology in the real world – automating the creation of new lifeforms

Synthetic biology is, quite literally, the creation of new genetic constructs and novel micro-organisms with innovative functions. Together with systems biology, it provides a platform for translating advances in genomics, proteomics and molecular biology into real-world applications.

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How to reliably get more data from less volume

The industrialization of biology has become possible thanks to the automation of repetitive tasks – such as liquid handling – making 24/7 operation feasible. This cost-saving automation addresses several major concerns for biology workflows.

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Effective sample preparation minimizes mass spectrometry maintenance

Testosterone levels are typically determined using automated immunoassay analyzers, but this has limitations. Liquid chromatography-tandem mass spectrometry (LC-MSMS) offers a selective and accurate alternative, and the Center for Advanced Laboratory Medicine at the University of California San Diego is using a novel extraction technology to automate sample preparation for this technique.

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Finding the perfect match

The success of hematopoietic stem cell donation is highly dependent on a close match between the donor and recipient human leukocyte antigen (HLA) alleles. DKMS Life Science Lab performs HLA typing of over a million potential donors a year, relying on automation to provide a cost-effective, high quality solution that delivers reliable high sample throughput.

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A (cyto)genetic revelation

Specialist laboratories engaged in molecular genetics and cytogenetics are turning to automation to cope with ever-increasing sample numbers, implementing tailored solutions designed to handle a range of materials and meet specific testing needs.

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A natural affinity

Receptor binding assays form an integral part of the preclinical screening service provided by Eurofins Pharma Discovery Services division. The first stage of the protocol is the transfer of tissue samples to a 96-well plate, a process that must be carefully performed to avoid any cross-contamination.

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Automation aids nationwide surveillance system for virus outbreaks

The Korea Center for Disease Control and Prevention (KCDC) in Seoul, Korea, conducts research to identify the etiology of communicable diseases and to find effective control, prevention, diagnosis and treatment for them.

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