Trio RNA-Seq incorporates proprietary technologies that generate RNA-Seq libraries from precious, low-input samples, while depleting abundant uninformative sequences. These powerful technologies include:
1) Chen, L., Liu, W., Zhang, Q., Xu, K., Ye, G., Wu, W., … Liu, Y. RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak. Emerging Microbes & Infections, 2020, 9(1), 313–319. doi: 10.1080/22221751.2020.1725399
2) Shen Z, Xiao Y, Kang L, et al. Genomic diversity of SARS-CoV-2 in Coronavirus Disease 2019 patients. Clinical Infectious Diseases. September 2020. doi:10.1093/cid/ciaa203
Two recent peer-reviewed studies (published in 2020) demonstrate the successful application of the Trio RNA-Seq Library Preparation Kit in detecting the novel coronavirus in patient samples:
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