Automating Functional Cell Based Bioassays: Turnkey Solution for Attaining Assay Reproducibility and Performance for Potency Testing Programs
In vitro functional bioassays are central to potency and stability testing programs for drug release, but require a high degree of precision and accuracy between experiments and operators. Automating these assays can increase throughput, reduce assay variability, decrease operational costs, and more importantly offer consistent method execution and transfer between sites. In this webinar we present automation of functional cell-based assays from Eurofins DiscoverX using Tecan’s newest generation of liquid handler, FLUENT. Case studies on automating DiscoverX’s cell-based assays that are routinely used for drug release will be discussed.
3 key words on the content:
QC Lot Release
Gaurav earned his Ph.D. in Cell and Molecular Biology from the Indian Institute of Science studying the activation mechanism of GPCRs. During his post-doc at the University of California San Diego, Gaurav discovered novel intracellular trafficking pathways essential for organelle biogenesis. At Eurofins DiscoverX, Gaurav is responsible for scientific integration and market development of the cell-based assays portfolio, and support method transfers to CROs for drug development programs for biologics and biosimilars.
Dr. Lucía Bruzzone is a product manager at Tecan. She studied molecular biology and biotechnology at the University of Buenos Aires in Argentina. During her PhD, she focused on cell biology and genetics at the Institut Jacques Monod in Paris, France. She joined Tecan in 2019 as an application specialist and focused on the development and support of applications on Tecan’s liquid handling platforms in the cellomics and proteomics area before joining the detection team in 2021.