The prep determines the result.

CONTACT US

Solid Phase Extraction

Solid Phase Extraction (SPE) is superior sample preparation method that efficiently concentrates analytes for downstream processes. By leveraging positive pressure processing, this technology can be easily automated and scaled without sacrificing extraction quality.

Tecan offers a wide variety of sorbent chemistries, volumes and configurations for columns and well-plates from large-scale single-well processing to 96-well µelution plates designed for reproducible workflows.

SPE new graphic

SPE columns and well-plates

Cons section_2

 

Tecan columns and well-plates can be packed with a variety of sorbents and chemistry blends providing effective capture of your desired compounds. In-house design, packing and quality controls ensure batch-to-batch consistency across formats leading to comparable recovery rates at scale. Read our poster presented at PEGS 2026 showing benchtop antibody purification across many of the formats described above.

Positive pressure processing

Resolvex® positive pressure processors offer significant advantages for column-based sample preparation including transferrable protocols, intuitive programming and scalability.

The unique design of Resolvex systems enables reproducible and consistent pressure application across columns and wells, even if one empties before the rest. This provides effective analyte clean-up reducing waste and sample loss in labs.

PPP

Resolvex processors

Inst Section (1)_72dpi

Intuitive lab solutions

By combining positive pressure processing with SPE, Tecan offers solutions from broad discovery to highly targeted validation assays at nearly every scale. Our intuitive sample preparation workflows streamline steps from on-column digestion and peptide desalting to automated antibody purification and enrichment. With precision built into every level – from small-scale manual methods to full automation on liquid handling platforms – Tecan solutions ensure reproducibility, reliability and confidence in your results.

Don’t take our word for it

See how researchers and scientists are using Tecan sample preparation solutions in their laboratories.

“In the past we sometimes had difficulties obtaining samples with sufficient volume for analysis, but the automated SPE workflow requires much smaller sample volumes, so we get accurate results even if we receive very little urine to analyze.”

- SYNLAB

“While the results of the manual and automated sample preparation were comparable, we found that the big advantage of using the Resolvex A200 was the amount of time we saved.”

- Pfizer

“We are extremely satisfied with the Fluent and Resolvex integration, and we haven’t even come close to the maximum throughput of the workflow yet, so we definitely have a lot of room to grow and increase our productivity.”

- FZJ

Customized SPE

For labs in need of specific manifold heights, column volumes, plate setups or for those just looking to push innovation further, Tecan offers customized benchtop positive pressure processors alongside tailored SPE consumables built exclusively for your lab. From minor software adjustments to a whole new SPE column, customizing a solution for your next set of samples can be delivered in as little as 14 days!

Simply reach out today letting us know you’d like to customize your next sample prep solution, and we’ll have an LC-MS expert dedicated to your lab’s needs and vision.

Experience the benefits of optimizing sample preparation for Biopharma industries.

Fill out the form below to receive more information from Tecan representative.

*Customer experiences reflect independent workflows developed and validated by the end user. Tecan products referenced above are intended for research use only and are not intended for use in diagnostic procedures.