Simplify Your Single Cell
Workflow Like Never Before●

Uno Single Cell Dispenser - Simple, gentle, fast, and more affordable than you may think.

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Introducing Uno: Streamline Your Single Cell Isolation Workflows​

The Uno Single Cell Dispenser™ is a compact, automated benchtop device engineered for simplicity. It accommodates a diverse range of applications—ranging from single-cell proteomics to iPSC libraries, 3D cell research and cell-line development, and beyond.

Uno gently and accurately dispenses single cells or reagents, delivering volumes from picoliters to microliters within minutes per 384 well plate.

Customer Interview

Professor Ryan Kelly from the Department of Chemistry and Biochemistry at Brigham Young University in Provo, Utah, discusses how the Uno Single Cell Dispenser enhances the accessibility of advanced biomedical research techniques for areas like cancer and developmental biology. The Kelly lab specializes in developing methods, instrumentation, and applications for comprehensive bioanalysis of trace samples, with a focus on applications in cancer and neurodegenerative diseases. They are particularly dedicated to single-cell and high-resolution spatial proteomics.

Episode 1: The complexity and challenges of cell isolation and sample preparation.

Episode 2: Cut down on lab time, not on quality. See how Uno makes it simpler.

Episode 3: Advanced proteomics research isn’t just for the big players. It’s for every lab.

Your needs at the core

Simple

Intuitive software and compact hardware at a competitive price. 

Fast

Isolate single cells in ~5 minutes, dispense reagents in <3 minutes across a 384-well plate and dispense up to 25 cells per well in one run.

Reliable

Based on HP’s proven microfluidic digital dispensing technology, a choice trusted by 1,000+ industry-leading customers.

Gentle

Maintain a robust 90% cell viability for downstream analysis. Compatible with a wide range of cells and reagents.

See what’s possible for you

Uno Single Cell Dispenser
 

  • Compatible with 12-384 plates
  • Customizable substrate, i.e., microscope slides

Uno Control Software
 

  • Setup a protocol in just minutes with easy fluid and plate definitions

C1a – Single Cell Dispensehead Cassette

  • Cell dispensing
  • Choose to dispense from 1 to 25 cells per well
  • 20 μl dispense reservoir

T1 / T1sf Dispensehead Cassette
 

  • Reagent dispensing
  • 11 pl minimum dispense volume
  • 20 μl dispense reservoir
  • T1sf: For aqueous solutions; requires no surfactant
  • T1: For DMSO, Acetonitrile, aqueous solutions with surfactant

D1 / D1sf Dispensehead Cassette
 

  • Reagent dispensing
  • 1 nl minimum dispense volume
  • 200 μl dispense reservoir
  • D1sf: For aqueous solutions; requires no surfactant
  • D1: For DMSO, Acetonitrile, aqueous solutions with surfactant

For research use only. Not for use in diagnostic procedures.

Resources

PUBLICATION

Nature Communications: One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes

PUBLICATION

​Easy and Accessible Workflow for Label-Free Single-Cell Proteomics.​

BROCHURE​

Simple. Fast. Gentle.​

Specifications

The simplicity of single cell isolation at your fingertips

Whitepaper

Generate CHO-K1 GFP-Expressing Cells for Cell Line Development Workflow

Whitepaper

Isolate Bright GFP-Expressing HEK-293 Cells for Cell Line Development Workflow

Whitepaper

The Uno Single Cell Dispenser - Cell Dispense Verification Method

Technical Note

Combining Uno Single Cell Dispenser™ and Spark® Cyto multimodeimaging reader to accelerate cell line development.

Protocol

Culture preparation protocol for dispensing of mammalian cells

Technical Note

Whole Transcriptome Amplification from Single Cells

Technical Note

A universal workflow approach for single-cell, mass spectrometry-based proteomics

Interested in learning more or have queries about the Uno Single Cell Dispenser?

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