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Männedorf, Switzerland, July 12, 2011 – The Protein Expression Purification Crystallization Core (PEPCC) at Case Western Reserve University, Ohio, is a state-of-the-art facility for high throughput protein crystallization, taking advantage of the automation capabilities of Tecan’s CrysScreen™ software and Freedom EVO® liquid handling platform to optimize crystallization parameters. Dr Harry Gill, Assistant Professor and Director of the PEPCC, explained: “Automation of high throughput crystallization trials is crucial, ensuring accurate pipetting while minimizing the amount of protein required for each experiment. We evaluated a variety of liquid handling systems when we set up the PEPCC, and the availability of the specialized CrysScreen software, together with the flexibility of the Freedom EVO platform, made the Tecan system an obvious choice for this role.”
“CrysScreen is fully integrated into the liquid handling platform’s Freedom EVOware® control software, providing fully automated design and preparation of optimization experiments in which crystallization parameters – such as pH, salt and precipitant concentration – are adjusted to improve crystal formation and quality. Thanks to CrysScreen, we are able to set up crystallization trials very quickly, achieving in minutes what would have taken almost a week to perform manually.”
To find out more about Tecan’s CrysScreen software, go to http://www.tecan.com/crysscreen
|Hanging drop module on Freedom EVO|
Tecan Trading AG
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Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics and clinical diagnostics. The company specializes in the development, production and distribution of automated workflow solutions for laboratories in the life sciences sector. Its clients include pharmaceutical and biotechnology companies, university research departments, forensic and diagnostic laboratories. As an original equipment manufacturer (OEM), Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2010, Tecan generated sales of CHF 371 million (USD 356 million; EUR 269 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TK: TECN/Reuters: TECZn.S/ ISIN: 1210019).