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Männedorf, Switzerland, May 14, 2013 – Legionnaires’ Disease has recently been in the headlines due to a number of serious outbreaks around the world. Researchers at the Ensminger Lab, part of the Department of Molecular Genetics at the University of Toronto, Canada, are using Tecan’s Infinite® M200 PRO plate reader and Gas Control Module (GCM™) to study host-pathogen interactions for Legionella bacteria. Alex Ensminger discussed the laboratory’s approach to studying this potentially deadly pathogen: “Legionella pneumophila normally grows inside amoebae and protozoa, and we need to understand how these pathogens interact with both their natural hosts and patients’ lungs. A key part of this research is to monitor bacterial growth under stable conditions, which is a very labor intensive process when performed manually.”
Alex soon identified an alternative: “I had seen recent publications describing the use of the Infinite M200 PRO to measure growth of Legionella, and as soon as I read that the GCM offered independent control of both O2 and CO2 levels within the measurement chamber, I was sold on buying one. I realized that I could put the bacteria in host cells, place them in the plate reader and leave them there for three or four days, watching their growth. By measuring every 20 minutes or so, we have seen growth curve shapes that disappear if readings are taken less frequently, even hourly. These shapes match what we might predict from cell biology, and allow more subtle distinctions between phenotypes than was previously possible.”
To find out more about the Infinite M200 PRO and GCM, visit www.tecan.com/gcm
Tecan Trading AG
Cornelia Kegele, Antonietta Allocca
Tel +41 (0)44 922 81 11
Fax +41 (0)44 922 81 12
Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics and clinical diagnostics. The company specializes in the development, production and distribution of automated workflow solutions for laboratories in the life sciences sector. Its clients include pharmaceutical and biotechnology companies, university research departments, and forensic and diagnostic laboratories. As an original equipment manufacturer (OEM), Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2011, Tecan generated sales of CHF 377 million (USD 424 million; EUR 306 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TK: TECN/Reuters: TECZn.S/Swiss security number: 1210019).