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ACEMBL is the first fully automatable pipeline for the production of multi-protein complexes, developed by researchers at the European Molecular Biology Laboratory (EMBL) on the Freedom EVO® platform from Tecan. This system makes it possible to perform experiments that were previously unthinkable using manual methods and has great potential for revealing currently unknown molecular mechanisms of health and disease that could be vital in drug discovery.
Dr Imre Berger, group leader, explained: “Automation is the essential solution for protein complex expression and production, when many-fold variation in the individual proteins is required for experimental success. With a robot, many experiments can be performed simultaneously and in parallel, with a precision that is unattainable manually. We use a Freedom EVO 200 platform with three identical liquid handling modules and, additionally, a sterile, covered compartment for growing cell cultures.”
To find out more on Tecan’s Freedom EVO, visit www.tecan.com/freedomevo
Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics, and clinical diagnostics. The company specializes in the development, production and distribution of instruments and automated workflow solutions for laboratories in the life sciences sector. With its subsidiary REMP (www.remp.com), Tecan is the market leader in automated laboratory storage and logistics systems. Its clients include pharmaceutical and biotechnology companies, university research departments, forensic and diagnostic laboratories. As an original equipment manufacturer, Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2009, Tecan generated sales of CHF 392 million (USD 361.2 million; EUR 259.6 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TK: TECN/Reuters: TECZn.S/ ISIN CH0012100191).
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