Researchers in the Department of Biosciences and Nutrition at the Karolinska Institute in Stockholm, Sweden, have been using Tecan’s Infinite® 200 microplate reader and NanoQuant Plate™ as one of the methods for the characterization of a newly isolated population of skin stem cells in mice (Lgr5+ cells).

Dr Maria Kasper, from the Karolinska Institute’s environmental toxicology group, explained how the system is helping the research: “The scarcity of Lgr5+ cells makes the extracted genetic material extremely valuable, so we need a method to achieve exact quantification of this RNA with minimal sample loss. Using our Infinite reader with the NanoQuant Plate ensures that only minimal material is required for reliable evaluation of our valuable RNA samples, and allows us to investigate more than 30 selected genes by qPCR from just 150 ng of isolated RNA.”

Maria’s colleague, Dr Viljar Jaks, continued: “Because the NanoQuant Plate is integrated into the Infinite microplate reader, it is very easy to use and the i-control™ software is intuitive. Having it in the laboratory has been very useful for our investigations.&rdquo

To find out more on Tecan’s Infinite 200 series microplate readers, visit www.tecan.com/infinite

To find out more on Tecan’s NanoQuant Plate, visit www.tecan.com/nanoquant

About Tecan

Tecan (www.tecan.com) is a leading global supplier of laboratory instruments and solutions for the biopharma, forensic and diagnostic industries. The company specializes in the development, production and distribution of automation solutions for life science laboratories. Through its REMP subsidiary (www.remp.com), Tecan is the premier supplier of automated laboratory storage and logistics systems. Tecan's clients include pharmaceutical and biotech companies, university research departments, diagnostic laboratories and companies as well as forensics laboratories. Founded in Switzerland in 1980, the company has production, research and development sites in both North America and Europe and maintains a sales and service network in 52 countries. In 2007, Tecan achieved sales of CHF 414.4 million (USD 345.3 million; EUR 252.7 million). Registered shares of the Tecan Group are traded on the SWX Swiss Exchange (TK: TECN/Reuters: TECZn.S/Valor: 1210019).

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