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October 21, 2014 | Customer News

Tecan’s AC Extraction Plate™ boosts productivity for clozapine testing at King’s College Hospital

October 21, 2014

Tecan’s AC Extraction Plate™ boosts productivity
for clozapine testing at King’s College Hospital

The AC Extraction Plate can help to streamline a variety of sample preparation workflows

Männedorf, Switzerland, October 21, 2014 – King’s College Hospital, London, has established a fully automated therapeutic drug monitoring protocol for clozapine using Tecan’s AC Extraction Plate™ and Freedom EVO® liquid handling platform. Lewis Couchman, Senior Clinical Scientist (Clinical Biochemistry Laboratory and Toxicology Department), explained: “We perform about 30,000 tests a year for clozapine, preparing the samples manually by liquid-liquid extraction. We wanted to automate the analytical process, making it more rapid and robust, and less prone to human error – as well as reducing costs and providing the capacity to grow the service – and the AC Extraction Plate and Freedom EVO have the potential to make a real difference to our workflow.”

“Currently, samples arriving at the laboratory by 1 pm are manually extracted during the afternoon, run overnight, and the results reported the following day. The Freedom EVO can prepare a whole AC Extraction Plate in around 30 minutes, followed directly by LC-MS analysis, with a runtime of just under four minutes a sample. We have compared around 500 samples prepared manually and using the automated method, and are really impressed with the results; there is no discrepancy between the two methods. We are in the final stages of the evaluation phase, but everybody is excited at the prospect of seeing it implemented.”

To find out more about Tecan’s AC Extraction Plate, visit www.tecan.com/acplate



For more information please contact

Tecan Trading AG
Cornelia Kegele, Antonietta Allocca
Seestrasse 103
CH-8708 Männedorf

Tel +41 (0)44 922 81 11
Fax +41 (0)44 922 81 12



About Tecan

Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics and clinical diagnostics. The company specializes in the development, production and distribution of automated workflow solutions for laboratories in the life sciences sector. Its clients include pharmaceutical and biotechnology companies, university research departments, and forensic and diagnostic laboratories. As an original equipment manufacturer (OEM), Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2013, Tecan generated sales of CHF 388 million (USD 419 million; EUR 316 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TECN; ISIN CH0012100191).