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April 17, 2012 | Customer News

Unwinding the genetic clock with Tecan’s Infinite® M1000 plate reader

D. melanogaster (left), classic model of genetics, compared to the housefly, Musca domestica

Männedorf, Switzerland, April 17, 2012 –
Tecan’s Infinite® M1000 plate reader has enabled researchers at the Institute of Entomology (ENTU), Czech Republic, to automate hourly luminescence measurement of transgenic Drosophila for the study of insect circadian clocks. Dr David Doležel, a researcher at ENTU, explained: “The expression of circadian genes is studied using transgenic Drosophila containing luciferase reporter genes controlled by the promoter of the gene under study. This requires a microplate reader that includes a luminescence module equipped with filters to discriminate between red and green luciferases, allowing us to follow multiple genes per well. Automatic plate transfer is also essential in order for measurements to be performed at regular intervals throughout the day and night.”


David continued: “The Infinite M1000’s compact size means that it fits easily into our laboratory incubator, so we can precisely control light and temperature and investigate the effect of environmental variables. Its microplate format allows us to load hundreds of flies into the plate reader at the same time, automating large-scale screens of mutant Drosophila strains and performing hundreds of measurements over a period of up to two weeks. Overall, we have been very impressed by the system’s performance and flexibility.”


To find out more about Tecan’s Infinite M1000 plate reader, visit www.tecan.com/infinitem1000


For more information please contact

Tecan Trading AG
Cornelia Kegele
Seestrasse 103
CH-8708 Männedorf

Tel +41 (0)44 922 81 11
Fax +41 (0)44 922 81 12



About Tecan

Tecan (www.tecan.com) is a leading global provider of laboratory instruments and solutions in biopharmaceuticals, forensics and clinical diagnostics. The company specializes in the development, production and distribution of automated workflow solutions for laboratories in the life sciences sector. Its clients include pharmaceutical and biotechnology companies, university research departments, and forensic and diagnostic laboratories. As an original equipment manufacturer (OEM), Tecan is also a leader in developing and manufacturing OEM instruments and components that are then distributed by partner companies. Founded in Switzerland in 1980, the company has manufacturing, research and development sites in both Europe and North America and maintains a sales and service network in 52 countries. In 2011, Tecan generated sales of CHF 377 million (USD 424 million; EUR 306 million). Registered shares of Tecan Group are traded on the SIX Swiss Exchange (TK: TECN/Reuters: TECZn.S/Swiss security number: 1210019).