Scientists at the Donnelly Centre for Cellular and Biomolecular Research have chosen generations of Tecan microplate readers to monitor the effects of environmental or drug perturbation on molecularly barcoded yeasts.
Legionnaires’ disease, a potentially fatal infection caused by Legionella pneumophila has recently been in the headlines due to a number of serious outbreaks around the world. Scientists at the University of Toronto are using Tecan’s Infinite® M200 PRO and Gas Control Module to study host-pathogen interactions for Legionella bacteria.
The Infinite® F500 is BioSentinel’s reader of choice for its high sensitivity botulinum neurotoxin assays. Intended for government laboratory and pharmaceutical screening applications, BioSentinel now recommends the Infinite F500 to all its customers, thanks to the reader’s combination of advanced features and competitive pricing.
A newly established research group in the Division of Microbiology at the University of Salzburg has chosen an Infinite® M200 PRO microplate reader for monitoring cell growth of microaerophilic bacteria in its work to investigate the pathogen Helicobacter pylori.
Researchers at the Lyon Neuroscince Research Centre benefitting from the flexibility and user-friendly design of the Infinite® 200 PRO multimode reader, and have developed a unique cell migration assay to help identify novel biotherapeutics for the treatment of gliblastoma.
Microbiologists at Giessen University are using an Infinite® M200 microplate reader to look at the potential of engineered metal nanoparticles for treating water, inhibiting the growth of bacteria in drinking water at the point of use, and eradicating pharmaceuticals and other micropollutants from waste water.
The Tecan Award 2011 built on last year's success and saw our customers submit a plethora of innovative applications for our detection equipment. Competition was fierce, with many ingenious entries, and third place was eventually awarded to Maria Isabel Pividori from the Universitat Autònoma de Barcelona, for her work on the detection of gliadin, a constituent of the cereal protein gluten.
Researchers at the Kyoto Institute of Technology chose Tecan's microplate readers and microarray processing instruments to develop highly sensitive immunodiagnostic technologies based on immobilized single-chain variable fragments (scFvs).
In the last edition of the Tecan Journal we announced the winner of the Tecan Award 2011, Svenja Kristina Holle from the University Hospital of Münster, whose team has developed an ex vivo method for investigating the dynamics of organic cation transport in proximal tubules of the kidney, using an Infinite® 200 PRO microplate reader.
The P4 Inserm-Jean Mérieux laboratory in Lyon relies on the flexibility, robustness and reliability of Tecan’s Infinite® 200 PRO monochromator-based microplate reader for absorbance-, luminescenceand fluorescence-based assays on Risk Group 4 pathogens. The P4 Inserm-Jean Mérieux laboratory in Lyon is a highly secure laboratory, the largest of its category in Europe, affiliated to the French National Institute of Health and Medical Research (INSERM), and open to national and international scientific teams that need to handle Risk Group 4 pathogens. P4’s main activities include diagnosis, research, biosafety and trainingon agents responsible for viral hemorrhagic fevers (Ebola, Marburg, Crimean-Congo hemorrhagic fever and Lassa) and fatal encephalitis (Nipah and Hendra).
Researchers at the Institute of Entomology (ENTU) in the Czech Republic are studying insect circadian clocks and have used Tecan’s Infinite® M1000 plate reader to automate hourly luminescence measurement of transgenic Drosophila. Automation enables large-scale screens of mutant Drosophila strains to be performed, involving hundreds of measurements over a period of up to two weeks.
Euroscreen is a pre-clinical drug discovery company based in Gosselies, Belgium, focusing on development of small molecule drugs for unmet clinical needs. Specializing in G-protein coupled receptors (GPCRs), Euroscreen works with a number of major pharmaceutical manufacturers to develop and optimize fi rst-in-class candidate compounds targeting GPCRs. In addition to its research activities, Euroscreen also operates a high throughput screening (HTS) service (Euroscreen FAST) providing customized GPCR screening and services for biotechnology companies and pharmaceutical manufacturers worldwide.
Scientists involved in the study of vitamin D levels in the Mongolian population were in need of a microplate reader to help further their research. Anamazing collaboration evolved, with staff from Tecan, CERLab, and Brigham and Women's Hospital working together to solve the problem.
Researchers at The Institute of Traditional Chinese Medicine and Natural Products, Jinan University, China, are using a Tecan multimode microplate reader to investigate the mechanism of immunosuppression caused by stress, aiming to discover effective natural solutions.
The inaugural Tecan Detection Award, designed to celebrate our customers’ innovation and ingenuity, received many strong entries. A very close contest eventually saw Dr Jeff Mumm from Georgia Health Sciences University (GHSU), US, awarded second place for his work on reporter-based drug screening using Tecan’s Infi nite® M1000 and live zebrafish!
Scientists from Affymetrix, Inc., a world-leading supplier of microarray equipment and assays, evaluated the Tecan Infinite® 200 NanoQuant multimode microplate reader and two other spectrophotometers for DNA concentration analysis in a new cytogenetic assay they have developed.
The Infinite® M1000 brings flexibility, sensitivity and speed in one high-end, multimode reader, bridging the gap between research, assay development and screening.
The Microbial Ecology and Host-Pathogen Interaction Laboratory (EMIP), of the INRA Institute in Montpellier, France, has already made great progress in research on virulence factors of insect pathogens, using Tecan’s monochromator-based Infinite™ M200 microplate reader.