When developing a liquid handling instrument, it is important to be first to market for early market leadership. Dr. Claudio Bui, Head of Product Concepts, Tecan, considers key elements to completing a project quickly and efficiently, including common pitfalls.
For patients in need of vital transplants, fast and accurate tissue typing can mean earlier treatment and a better chance of survival. Next generation sequencing (NGS) is revolutionizing human leukocyte antigen (HLA) typing by providing allele-level resolution in a single high-throughput step.
They don’t take up much room in your DNA – a mere 4 megabases on the short arm of Chromosome 6 – but Human Leukocyte Antigen (HLA) genes play a defining role in whether you will develop an autoimmune disorder, fend off an infectious disease, or have an adverse reaction to potentially life-saving treatments.