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By Ashesh Saraiya
NGS has transformed genomics research and contributed to breakthroughs in many areas of medical science. At the same time, making NGS robust, reliable and cost-effective can be challenging for many labs. In particular, generating...
In true holiday spirit, isn't it time we spoke the truth about the toll next generation sequencing (NGS) is taking on your lab? Yes, NGS is a revolutionary technology that can help you break new ground in your research, but when...
By Beatrice Marg-Haufe
One of the steps in DNA sample preparation that is often overlooked when moving from manual to automated methods, is the quantification and normalization of nucleic acid samples that are destined for downstream analysis in...
By Beatrice Marg-Haufe
Written in collaboration with Zymo Research, Irvine, CA, USA.
Next-generation sequencing (NGS*) has revolutionized genomic research, allowing entire genomes to be sequenced in a single day. This has led to massive advances in...
By Beatrice Marg-Haufe
Written in collaboration with Zymo Research, Irvine, CA, USA.
With the advent of next-generation sequencing (NGS), the field of metagenomics has exploded in recent years, as scientists are now able to study microbes as...
By Alexandra Sommer
The drive to make healthcare more targeted and more personalized has accelerated the application of increasingly sophisticated technologies, such as next generation sequencing (NGS). The result has been the introduction of some...
By Rick Luedke You may be convinced that your academic research laboratory is humming along just fine and cannot benefit from, take the time to consider, and perhaps most of all, afford adding automation to your workflow.
By Jon Smith
If you’ve decided to take advantage of next generation sequencing (NGS) for HLA typing, your timing couldn’t be better. With the recent introduction of more affordable bench-top sequencers and targeted HLA sequencing panels, NGS is more...
By Severin Heynen
With multiple tests to perform on a tiny volume, samples are getting more precious. And as Next Generation Sequencing pushes the envelope on cost and throughput, scientists are looking for ways of reducing reagent volumes without...
By Jon Smith
For patients in need of vital transplants, fast and accurate tissue typing can mean earlier treatment and a better chance of survival. Next generation sequencing (NGS) is revolutionizing human leukocyte antigen (HLA) typing by providing...
By Jon Smith
They don’t take up much room in your DNA – a mere 4 megabases on the short arm of Chromosome 6 – but Human Leukocyte Antigen (HLA) genes play a defining role in whether you will develop an autoimmune disorder, fend off an infectious...
By Achim von Leoprechting
Next-generation sequencing (NGS) is poised to become a decisive tool in diagnostic, therapeutic, and prognostic applications in oncology. In the first part of this two-part series, we saw that sequencing tumor-derived DNA...
By Achim von Leoprechting
Massively parallel sequencing has rapidly become a must-have tool of the trade in molecular biology and drug discovery research. In recent years, the cost of next-generation sequencing (NGS) has declined exponentially,...