Trauma is the main cause of premature death internationally, resulting in more deaths in people under 40 years old than all other causes combined. Even trauma victims receiving hospital care have a high mortality rate, in part due to massive systemic inflammatory reactions leading to the dysfunction of organs that were not initially injured. A team at Oslo University Hospital in Norway has been investigating the role of the protein HMGB1 (High Mobility Group Box 1) in the development of trauma pathologies and its potential as a clinical biomarker or therapeutic target in these cases.
Blood testing is ideal for a wide range of analytes, but it has limitations for hormone analysis. In Canada, FLUIDS iQ has turned to saliva as an alternative test matrix, which is proving an excellent choice for measuring the bioavailability of a range of hormones in the wellness arena.