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Tecan Journal

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Planning ahead: looking beyond the initial costs of instrument development

Bringing a novel life sciences or diagnostics instrument to market is a lengthy and costly undertaking, requiring years of planning and execution. Companies understandably focus much of their energy on initial concept development and reducing the...

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Collaborating to alleviate flow cytometry bottlenecks and foster business growth

Designing and developing a novel lab instrument is a massive undertaking, requiring extensive resources and personnel over multiple years. Many companies therefore choose to partner with an OEM instrument developer to free up internal resources,...

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Delivering rapid results at the point of patient care

TOPMEDLAB Medical Technology has developed an innovative, immunofluorescence analyzer to meet point-of-care testing needs. This user-friendly instrument offers rapid results and is easy to maintain, making it ideal for situations where time is of...

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Measuring sIL-2R Levels In Interstitial Lung Disease

St Antonius Hospital in Nieuwegein, the Netherlands, uses a soluble interleukin-2 receptor (sIL-2R) ELISA from Tecan in the investigation, management and monitoring of interstitial lung disease. This easy-to-use assay is the world’s first...

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Opening The Door To Single-cell Proteomics

The quantification of unique proteins within biological samples has traditionally required thousands, tens of thousands or even millions of cells, with no way to identify cellular heterogeneity within the populations. To overcome this issue,...

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State-of-the-art Automation Unlocks New Possibilities For Vaccine Development

The vaccine development process has transformed dramatically in recent years, driven by the urgent need for effective immunization against emerging contagious diseases. Traditional pipelines for the creation of novel vaccines relied on more than 10...

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Streamlining Workflows For Australia’s Largest Pathology Provider

Pathology is at the core of diagnostics, and obtaining reliable and timely results requires quick and accurate liquid handling. With laboratories often being pushed to their limits, automation can lend a helping hand and provide the ability to adapt...

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Flexing Automation Capabilities

Many diagnostic laboratories rely on PCR-based tests to identify a range of illnesses, from gastrointestinal and respiratory infections to tropical diseases. However, processing the samples manually can be time consuming and prone to errors,...

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Powering Next Generation Genomics

Spatial genomics is a rapidly growing field, allowing researchers to explore gene expression in the context of tissue location. Vizgen has developed the MERSCOPE® Platform, the first commercial high multiplexing, high resolution in situ solution to...

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Seeing is believing: harnessing the power of automation in single-cell genomics workflows

The prevalence of eye diseases is rising around the world and, for most of them, there are no effective therapies available. Disorders that impair vision – such as macular degeneration or glaucoma – are a leading cause of disability and loss of an...

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Dramatically increasing throughput and efficiency of SPR analysis to accelerate drug discovery

Surface plasmon resonance biosensors have become the go-to technology for drug discovery in the pharmaceutical and biotechnology sectors, offering label-free, real-time measurements that characterize the interactions of nearly any molecular system....

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Automating microbial strain development for a sustainable future

Transitioning from the world’s current petroleum-based industry to a sustainable bioeconomy depends upon the microbial upcycling of plant-based feedstocks for monomer production. Researchers at Forschungszentrum Jülich (FZJ) in Germany have...

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High speed immunodiagnostics with multicolor imaging

FantasiaBio, based in the Jinhua region of China’s Zhejiang province, understands the power of imaging live cells, and has created a range of fluorescence-based tools to exploit the power of multiplexed live cell imaging for clinical research and...

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Diagnosing hormone-based disorders using saliva

Diagnosing hormone-based disorders using saliva samples dates back to the 1980s, but it is only the sensitivity improvements over the last decade that have led to saliva-based diagnostics becoming a viable alternative to blood testing. Biovis’...

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Working together to untangle IVDR

The European Union’s In Vitro Diagnostics Regulation (IVDR) replaces the In Vitro Diagnostic Medical Devices Directive (IVDD), completely overhauling the regulations regarding pre- and post- market requirements for IVD devices. This has implications...

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Building capabilities in optical genome mapping – going beyond next-generation sequencing

Large structural variations in the genome are responsible for many diseases and conditions, including cancers and developmental disorders. Gene changes – including insertions or deletions, translocations, inversions and duplications – can lead to...

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Partnering for progress in oncology

Tecan recently teamed up with Nature Medicine to host a symposium on the latest ground-breaking research into cancer diagnosis and treatment, from novel biomarkers to personalized vaccines and cell-based therapies. A select group of industry leaders...

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Analyzing poor quality RNA: how low can you go?

NGS is a vital tool used for studying the structure and function of DNA for multiple applications. However, there are several challenges commonly encountered when using this technique, particularly when working with degraded or trace levels of RNA....

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Tecan Gives Back initiative supports research into cancer prevention

Tecan Gives Back is an employee-driven initiative supporting charities that help to improve people’s health and quality of life. Created as part of the company’s 40th anniversary celebrations, the scheme gives employees the opportunity to earn...

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Novel methods guiding cancer treatment

Multiple myeloma (MM) remains an incurable blood cancer, but recent advancements in treatment have significantly improved patient prognosis and quality of life. UK-based specialist diagnostic company The Binding Site has developed a new strategy...

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Improved prostate screening to help men live long and prosper

Prostate cancer is the second most common cancer in men, killing hundreds of thousands each year. However, the current routine screening method for checking prostate-specific antigen (PSA) levels generates false positives in an alarming number of...

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Taking new cancer cures from bench to bedside

Many of the anti-cancer drugs currently used for chemotherapy work by causing replication-associated DNA damage that kills individual cancer cells. While this can be an effective way of treating the disease, the drugs often also indiscriminately...

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High throughput automation and genomics for an antimicrobial resistance surveillance system for diverse applications

Dr Sam Abraham is an associate professor at Murdoch University, Australia, with a research interest in antimicrobial resistance and drug discovery. His presentation at Tecan’s virtual Genomics Symposium can be viewed here.

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Supporting Zika virus drug screening in Brazil

Several outbreaks of the Zika virus have been reported around the world since its discovery in 1947, but a commercially available treatment for the disease is still not available, and scientists continue to search for the best antiviral agent....

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Revolutionizing long DNA synthesis by speeding up the process

Synthetic DNA has become the central component of countless scientific and technological innovations across many applications, from biopharmaceuticals to biofuels. However, research and drug development pipelines are often hindered by the cost and...

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Salivary stress biomarkers to nose out the benefits of healthcare clowning to children with psychiatric disorders

Several studies have shown that healthcare clowning has a strong positive effect on pediatric patients in general, but there is limited research into its impact on those with psychological disorders. RED NOSES Clowndoctors Austria – an organization...

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A dream team for bioanalytical drug testing

9-Delta Analytical LLC in California provides independent forensic and clinical toxicology testing services for academic research groups, non-profit organizations and governmental agencies across the USA and Canada. Focusing mainly on human samples,...

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Improving speed and accuracy of biomanufacturing for more rapid and cost-effective therapies

The biomanufacturing industry is constantly on the lookout for new technologies to improve the speed, accuracy and performance of its processes, particularly in the biologics arena. Biotechnology company ValitaCell has embraced this challenge,...

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A voyage of discovery: exploring the role of HMGB1 in trauma pathology

Trauma is the main cause of premature death internationally, resulting in more deaths in people under 40 years old than all other causes combined. Even trauma victims receiving hospital care have a high mortality rate, in part due to massive...

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Fighting the opioid epidemic by reducing manual labor and increasing throughput

Opioid addiction, alongside addiction to other substances, is a significant public health, social and economic challenge in the US. In 2017, the opioid epidemic was declared a public health emergency by the Department of Health and Human Services,...

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Quality food and feed enzyme development at the industrial scale

The use of enzymes as biocatalysts in industrial applications has steadily gained popularity, as it offers an efficient way to use raw materials while minimizing waste. This approach has been successfully scaled for commercial processes in the...

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Trust your gut – advances in microbiome DNA analysis

The human gut microbiome has been found to affect metabolic health and nutrient absorption, and preliminary research also suggests that it contributes to the development of the immune response, food allergies and intolerances, obesity, and a wide...

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Generating a cellular infection model for monitoring SARS-CoV-2 replication

Work to characterize and further understand the molecular pathology of SARSCoV- 2 became a focus for many virology departments following the identification of the novel virus responsible for COVID-19. Drs Marek Widera, Alexander Wilhelm and...

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Automating a herd of tests

The COVID-19 pandemic is an important reminder that pathogens are not only transmitted via air and contact with other humans, but also from animals and through food. This highlights the need for effective diagnostic tools that offer fast testing of...

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Exploring zoonotic pathogens in Australian livestock

Antimicrobial resistance is a growing issue preventing the effective treatment of numerous parasitic diseases in both humans and animals. The lack of effective antimicrobials for the treatment of a growing number of diseases represents a serious...

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Mitosis as a potential therapeutic target for cancer? A divided topic

Mitosis plays an essential role in growth and cellular replacement, and is often dysregulated in cancers, making the process of therapeutic interest. Researchers at the University of North Carolina at Chapel Hill (UNC Chapel Hill) are developing...

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Pumping a way for effective gas emission monitoring

Continuous emission monitoring systems that detect gases or particulate matter concentrations are important in various industrial settings, where they are used to ensure that potential sources of pollutants comply with environmental regulations....

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Tecan acquires medical device specialist Paramit

Paramit Corporation is the latest company to join the Tecan Group, bringing with it a wealth of knowledge and experience, as well as a fresh perspective to engineering and manufacturing, that will resonate throughout the whole organization. Paramit...

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