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Rheumatoid arthritis, type 1 diabetes and celiac disease are familiar examples of autoimmune disorders that occur when the immune system attacks healthy cells or tissues by mistake. Myasthenia gravis is a far rarer autoimmune disease, causing...
Extracellular HMGB1 has been implicated in a wide range of conditions, from trauma and sepsis to epilepsy and lupus. As a result, this almost ubiquitous biomolecule is garnering increasing interest as a potential target for new therapeutics. In a...
Many people in the life science and medical communities will never have heard of HMGB1 or, to give it its full title, high mobility group box 1 protein. Despite this, it is the most common nuclear protein after the histones – with around a million...
The Monash Antibody Technologies Facility (MATF) in Victoria, Australia, has added a new dimension to its high throughput service, off ering screening for antibody functionality. This time-consuming phase is crucial for many projects, and can now be...