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Multiple myeloma (MM) remains an incurable blood cancer, but recent advancements in treatment have significantly improved patient prognosis and quality of life. UK-based specialist diagnostic company The Binding Site has developed a new strategy...
Prostate cancer is the second most common cancer in men, killing hundreds of thousands each year. However, the current routine screening method for checking prostate-specific antigen (PSA) levels generates false positives in an alarming number of...
Synthetic DNA has become the central component of countless scientific and technological innovations across many applications, from biopharmaceuticals to biofuels. However, research and drug development pipelines are often hindered by the cost and...
The use of enzymes as biocatalysts in industrial applications has steadily gained popularity, as it offers an efficient way to use raw materials while minimizing waste. This approach has been successfully scaled for commercial processes in the...
The COVID-19 pandemic has forced everyone to look at laboratory routines to see if they are really pandemic proof. For example, the explosive demand for high throughput genomic analysis often creates upstream pressures to process many more samples...
SARS-CoV-2 has hit the world by storm and testing has had a major part to play in the fight against the virus, helping to track cases and slow rates of infection. ABC Labs, based at the Karolinska campus in Stockholm, was founded soon after the...
Hormones are specialist chemical messengers that provide a communication system between different parts of the body. They affect everything from growth and metabolism to appetite and mood, while also playing a vital role in puberty and fertility....
Cell culture is at the heart of the production process for many biopharmaceuticals, but finding the optimal conditions to maximize yield can be a complex and time-consuming process. Traditional process development relies on costly and...
The ever-increasing throughput and ever-decreasing cost of next generation sequencing have made this technology a practical and affordable solution for everything from molecular diagnostics and antimicrobial susceptibility testing to crop research...
Recent viral outbreaks have alerted the world to the serious consequences of viral disease, yet the development of new antiviral drugs is challenging because of problems such as resistance or lack of molecular targets. Researchers at Zhejiang...
Understanding how and when laboratory automation assets are being used is crucial to maximize productivity and enable effective resource planning in high throughput facilities. California’s Ambry Genetics has a portfolio of almost 60 Fluent® and...
GAP Peptides has developed a novel approach to synthesizing high crude purity peptides that minimizes solvent and raw material consumption, while simultaneously reducing waste. Laboratory automation is helping this start-up company to accelerate its...
Genetic testing is at the forefront of modern medicine, and powerful tools are now available to identify inherited DNA characteristics that are potentially detrimental to health or conversely show susceptibility to targeted therapies. One such...
Stem cell research has seen explosive growth in recent years, with the technology holding promise for the treatment and cure of a wide range of conditions, from cancer, diabetes and heart disease to neurological conditions, inherited disorders and...
The initial screening of chromatographic conditions can be a major bottleneck in the development of protein purification protocols. Italian company BiCT – Biological and Chemical Technologies – has turned to automation to overcome this issue,...
Quality control of milk is important to ensure compliance with regulations and to support dairy farmers in their herd management. However, analyzing multiple milk samples from many individual cows is a time-consuming process. French laboratory...
Detecting adverse off-target effects is crucial to ensure the safety of potential therapeutics, but limited throughput and ethical considerations have traditionally forced pharmaceutical companies to perform safety pharmacology studies at a late...
Automated laboratory workflows are commonplace in the pharmaceutical sector, offering increased throughput and process security throughout the drug discovery process. Most of these systems are dedicated to a specific task or assay, and have been...
Clinical diagnostics company Ambry Genetics focuses on the identification of germline mutations, detecting large deletions and duplications primarily by next generation sequencing. Automation holds the key to efficient high throughput assays,...
Access to human pluripotent embryonic stem cells is enabling Genea Biocells to pioneer novel therapies to treat a number of neuromuscular diseases. Drawing on almost 30 years of research heritage, the company is using its expertise to model spinal...
The rising global problem of antimicrobial resistance has led to growing pressure on food producers to eliminate the use of prophylactic antibiotics as an additive in livestock feeds. To help combat the potential risk this poses to animal health,...
Microbiome research is still in its infancy, with little currently understood about the role micro-organisms play in both maintaining our day-to-day health and the genesis of disease. Researchers at the Karolinska Institute are using next generation...
Maintaining a flexible approach can be difficult in biopharmaceutical research; core laboratories must balance the ability to adapt to individual project requirements with the need for efficient, high throughput processing of ever-increasing sample...
The biosimilars market is expanding rapidly as the patents expire for an increasing number of high profile biopharmaceutical agents. The complex nature of biologics requires extensive characterization of the production techniques and in vivo effects...
The industrialization of biology has become possible thanks to the automation of repetitive tasks – such as liquid handling – making 24/7 operation feasible. This cost-saving automation addresses several major concerns for biology workflows.
The Monash Antibody Technologies Facility (MATF) in Victoria, Australia, has added a new dimension to its high throughput service, off ering screening for antibody functionality. This time-consuming phase is crucial for many projects, and can now be...
The Institute for Product Quality, based in Berlin, has grown into a service laboratory that provides virtually any and every test required by the food market, from microbiology to pesticide testing. Using its expertise in food analytics and kit...
Dart NeuroScience specializes in the development of novel therapeutics targeting neurological disorders, with an emphasis on impairment of cognitive functions such as memory.