Selected issue: 1/2023

Tecan Gives Back is an employee-driven initiative supporting charities that help to improve people’s health and quality of life. Created as part of the company’s 40th anniversary celebrations, the scheme gives employees the opportunity to earn ‘kilometers’ for their chosen charity by engaging in fitness and wellness activities, or by volunteering. These are then pooled and converted into cash donations at the end of the month-long challenge. One of this year’s beneficiaries is World Cancer Research Fund (WCRF), a global research charity focused on reducing the risk of developing cancer and improving the outcomes for those already diagnosed.

Multiple myeloma (MM) remains an incurable blood cancer, but recent advancements in treatment have significantly improved patient prognosis and quality of life. UK-based specialist diagnostic company The Binding Site has developed a new strategy that monitors pre-cancerous conditions associated with MM as well as treatment success, helping to guide therapeutic pathways with more accurate information.

Prostate cancer is the second most common cancer in men, killing hundreds of thousands each year. However, the current routine screening method for checking prostate-specific antigen (PSA) levels generates false positives in an alarming number of cases, leading to thousands of unnecessary biopsies each year. To combat this, Life Length has developed ProsTAV®, a state-of-the-art in vitro diagnostic test that uses telomere associated variables (TAVs) to identify patients with a higher risk of prostate cancer, aiding screening initiatives and reducing the number of unnecessary biopsies

Many of the anti-cancer drugs currently used for chemotherapy work by causing replication-associated DNA damage that kills individual cancer cells. While this can be an effective way of treating the disease, the drugs often also indiscriminately affect healthy cells, causing unpleasant side effects for the patient. To help resolve this problem, researchers at the Karolinska Institute in Sweden are developing DNA repair inhibitors that are able to selectively introduce toxic DNA damage to cancer cells, while avoiding causing harm to normal cells, to support the successful treatment of cancers and improving patients’ experience of chemotherapy.