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Selected category: Clinical Diagnostics

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Taking a Fluent® approach to genetic screening

Clinical diagnostics company Ambry Genetics focuses on the identification of germline mutations, detecting large deletions and duplications primarily by next generation sequencing. Automation holds the key to efficient high throughput assays, ensuring optimum productivity.

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Time saved in diagnostic vitamin B testing

Mass spectrometry is rapidly becoming the method of choice for quantitative analysis of micronutrients such as vitamins B1, B6, B12 and D, as well as for steroids, hormones and many other drugs. For clinical laboratories, the bottleneck of MS-based techniques is not the analysis, but the pre-processing of the samples to remove proteins and other biological molecules that could interfere with the results.

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Effective sample preparation minimizes mass spectrometry maintenance

Testosterone levels are typically determined using automated immunoassay analyzers, but this has limitations. Liquid chromatography-tandem mass spectrometry (LC-MSMS) offers a selective and accurate alternative, and the Center for Advanced Laboratory Medicine at the University of California San Diego is using a novel extraction technology to automate sample preparation for this technique.

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Automation – an extension of the analyst

Reputation and accreditation are essential for clinical reference laboratories, helping to win new business and ensure a steady flow of work from existing customer labs. With diagnostic testing demands increasing year-on-year, Carpermor continually invests in cutting-edge assays and state-of-the-art laboratory automation to maintain the quality and efficiency of its services.

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Consistency for a changing market

PerkinElmer Healthcare Diagnostics (Shanghai) Co develops and manufactures instruments for the processing and analysis of clinical samples in hospital laboratories across China. A pioneer of time-resolved fluorescence techniques in this market, the company prides itself on creating cutting-edge automated solutions to address unmet needs in infectious disease diagnostics.

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Fungal detection accelerated

Chinese IVD company Dynamiker has developed a range of rapid diagnostic kits to help address the rising problem of invasive fungal diseases in hospitals. Offering results in under two hours, these colorimetric and ELISA assays are designed to address the problems associated with traditional diagnostic techniques – poor sensitivity and slow turnaround times – allowing earlier implementation of antifungal treatments for better patient outcomes.

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Liquid biopsies made easy

VolitionRx is using ist proprietary Nucleosomics® technology platform to develop a range of diagnostic assays for cancer and other conditions, creating non-invasive tests that identify disease-specific nucleosome signatures circulating in the blood.

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Providing diagnostic solutions for Alzheimer’s disease

AIBL International, the latest addition to the Tecan Group, offers a range of microplate-based immunoassays to help diagnose Alzheimer’s disease, a devastating condition that significantly impacts the lives of both sufferers and their families. Early diagnosis is essential for implementation of appropriate treatment and support mechanisms, enabling patients to live as independently as possible.

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A helping hand for vitamin testing

A Freedom EVO® workstation is proving key to the provision of high quality vitamin testing services at the Medical Laboratories of the Reinier de Graaf Hospital. This versatile solution has enabled full automation of the majority of sample preparation workflows for LC analysis of vitamins, generating major time and cost savings, and meeting the laboratory’s increasing throughput demands.

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Simplicity by design

Genera Biosystems has been testing a HydroSpeed™ plate washer with its Sirocco™ multiplexed diagnostics automation platform, allowing rapid, efficient washing of its proprietary AmpaSand™ beads for high retention rates and accurate results.

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An important piece of the HIV puzzle

The Irkutsk Regional AIDS Center is taking advantage of the flexibility and ease of use of an Infinite® 200 PRO multimode reader to help monitor HIV patients. Combining luminescence- and absorbance-based assays with a range of other diagnostic tests, the Center is able to accurately assess the immune status of its patients.

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Stressing the importance of quality assays

The Department of Psychology at TU Dresden is taking advantage of the quality and reproducibility of various IBL International immunoassays – including the Cortisol Saliva Luminescence Immunoassay – to investigate the link between steroid hormones and stress.

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Streamlining medical genetics with the aid of automation

With an ever-increasing workload, Germany’s Munich Leukemia Laboratory has automated its cytogenetics protocols on five Freedom EVO® workstations, enabling leaner, standardized, more efficient processing and minimizing the potential for human error.

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Automation helps enhance diagnostics protocols

The Molecular Biology Department at Colombia’s Laboratorio Clinico Medico Colcan is using a Freedom EVO® 150 liquid handling platform to automate its nucleic acid extraction and real-time PCR protocols, offering increased flexibility and helping to improve sample throughput.

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Cavro® ADP a hit with Chinese in vitro diagnostic customers

Chinese company DaAn Gene has integrated the Cavro Air Displacement Pipettor (ADP) into its new generation of molecular diagnostic instruments, bringing the advantages of Tecan’s liquid pipetting expertise to blood banks and infectious disease laboratories in China.

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Automation allows simultaneous antimicrobial susceptibility testing and MALDI-TOF sample preparation for bacterial identification

A Freedom EVO®-based platform for automated antimicrobial susceptibility testing and MALDI-TOF sample preparation is proving beneficial to the Medical Laboratory Bremen, offering enhanced reproducibility compared to manual processes and greater accuracy of results.

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A complete solution for ELISA processing

MLM Medical Labs is taking advantage of the Freedom EVOlyzer® workstation’s optimized ELISA processing to help meet the complex laboratory support needs of clinical trials, increasing throughput and improving process security.

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Making transfusion even safer with blood genotyping

AXO Science has established a Freedom EVO®-based high throughput blood genotyping system, helping to meet the needs of blood banks and transfusion centers around the world.

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Automation helps to improve in situ hybridization protocols

The pathology laboratory at Shanghai’s Changhai Hospital has successfully evaluated Tecan’s HS 400™ PRO hybridization station for the analysis of breast and lung cancers.

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Automation increases neonatal screening throughput

Astoria-Pacific International has chosen the Freedom EVOR liquid handling platform to automate its SPOTCHECKR Neonatal Screening assays for biotinidase and GALT (galactose-1-phosphate uridyltransferase).

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High throughput HIV screening with Freedom EVOlyzer®

ViroMed, a provider of laboratory testing services based in Minneapolis, USA, chose six Freedom EVOlyzers to support high throughput ELISA testing for a substantial HIV screening project.

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Walkaway automation for infectious disease testing

Vestfold Hospital Trust in Norway has chosen the Freedom EVOlyzerR for automation of ELISA assays in its microbiology laboratory in Tonsberg.

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Fully automated ELISA testing in veterinary diagnostics

The Insitut Galli-Valerio in Lausanne, Switzerland, has chosen a Freedom EVO® platform to fully automate all ELISAs for the Swiss authorities' ambitious program to eradicate bovine virus diarrhea virus (BVDV), which can cause mucosal disease in cattle.

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A long-standing partnership with success

Inverness Medical has been using Tecan liquid handling systems to automate ELISA testing in Spain for over 15 years. The Company supplies Tecan instruments free of charge to hospitals and laboratories using its diagnostic kits and reagents, an agreement which has been benefiting its customers since 1990.

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Pre-analytics made even easier

Gruppo MultiMedica has been using Tecan's FE500 preanalytical workstation to provide automated sample sorting and processing since October 2003, and has now upgraded to the FE500pro™ for even greater flexibility.

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Checking out what's checking in

Scientists at the Animal, Plant and Foodstuffs Inspection Center in Tianjin, China, are using a Freedom EVOlyzer® workstation to help monitor livestock entering the municipality for the presence of infectious diseases.

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Reliable and time-saving diagnostic ELISA tests

Automation of nine ELISA based serological tests for autoimmune and infectious diseases on the Freedom EVOlyzer® platform has saved Unilabs AB, Skovde, Sweden, a lot of labor, releasing valuable time for other activities.

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Pre-analytics made easy

The clinical laboratory at Fletcher Allen Health Care is the reference diagnostic center for the entire state of Vermont and, to ensure a high throughput capacity, uses Tecan’s Genesis FE500™ to automate pre-analytical sample processing.

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Tecan automation streamlines veterinary diagnostics processes

In order to increase reliability, efficacy and throughput of its diagnostic services, the Landeslabor Berlin-Brandenburg (LLBB) in Frankfurt (Oder), Germany, has chosen Tecan’s liquid handling workstations to automate the process flow of serological sample analysis.

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High throughput EIAs with Freedom EVO® Clinical

Laboratory services company synlab offers analysis of human, animal and environmental samples and, at its Augsburg site in Germany, it has chosen two Freedom EVO® Clinical workstations in combination with the BEP® III system from Siemens to process an enormous throughput of EIAs to diagnose infectious diseases.

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Efficiency by automation - high throughput sample processing

The diagnostics laboratory at the Catholic Medical Center (CMC) in Manchester, New Hampshire, USA, has chosen the Genesis FE500™ platform to automate sample handling, successfully turning its ‘stat lab’ into a full service laboratory and processing three times the previous volume in the same laboratory space.

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Automated pre-analytical blood sample sorting

The Sahlgrenska University Hospital in Gothenburg – one of the largest hospitals in Sweden – is saving considerable time using a Genesis FE500™ workstation for the pre-analytical processing of blood samples.

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Automated virus testing in animals

Scientists at the Staatliches Veterinäruntersuchungsamt (National Veterinary Laboratory) Arnsberg in Germany, responsible for veterinary diagnoses, have chosen Tecan’s Freedom EVO® workstation for the rapid detection of viruses which cause potentially devastating diseases.

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Freedom EVOlyzer® received with great enthusiasm in Spain

The Freedom EVOlyzer, Tecan’s new generation of automated ELISA systems, has proved to be increasingly popular with laboratories throughout Spain since being introduced to the country in July 2006 by Inverness Medical Iberica (IMI), one of Tecan’s principle diagnostic distributors for the area.

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Automated blood pooling ensures safe PCR diagnostics

The Blood Donor Center in Halle, Germany, is using the Freedom EVO® Clinical 150 with integrated Te-PoolSafe™ module for safe and reliable automated pooling of blood for subsequent PCR-based testing, ensuring that blood products are free of infection.

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High throughput diagnosis of infectious animal diseases with the Freedom EVOlyzer®

The Swedish National Veterinary Institute (SVA) in Uppsala, Sweden, depends on a Tecan Freedom EVOlyzer® for automating ELISAs during routine diagnostic screening of animal diseases such as Porcine Reproductive and Respiratory Syndrome (PRRS).

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Evaluating automated nucleic acid extraction using Abbott RealTime™ assays

Tecan’s Freedom EVO® Clinical 75 performs fully automated RNA and DNA extraction from up to 24 samples in 3 hours, using magnetic microparticle processing. The Laboratory LABCONOWL in Bad Salzuflen, Germany evaluated the instrument’s performance in combination with the Abbott RealTime™ HIV-1 and HCV assays, and compared it to the previously validated Abbott m2000™ processing system.

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Te-PoolSafe™ boosts pipetting accuracy for testing donor blood

The German Red Cross Institute in Frankfurt is responsible for screening thousands of donated blood samples every day for blood banks in Germany and further afield. Scientists at the Institute have developed high throughput PCR-based testing methods to screen for a number of viruses, and samples are pooled prior to screening using three Tecan liquid handling workstations.

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