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Targeted protein degradation (TPD) is growing to be one of the most promising therapeutic approaches to targeting previously undruggable proteins involved in many different diseases. For this purpose, different classes of molecules are being...
Detecting endotoxins is of paramount importance to certify that a product is free of bacterial contamination. Endotoxins are lipopolysaccharides (LPS) that can be found on the outer membrane of certain gram-negative bacteria such as E. coli. The...
Carbonic anhydrases (CAs) catalyze the reaction between water and carbon dioxide to regulate pH and fluid balance in vivo. Deviations in CA activity have been shown to correlate with bone, lung and liver diseases, as well as obesity, type II...
In a post-pandemic world, the need for real-time and remote connectivity is more crucial than ever. Today’s laboratory equipment and analyzers are capable of generating more data than ever before, creating new challenges for data processing and...
The Health Psychology Lab at Brandeis University in the USA is using gold standard luminescence assays to monitor cortisol and other salivary biomarkers of stress. In addition to its own research projects, the Health Psychology Lab offers assay...
Genetic modification of mammalian cells is now a routine daily activity in academic and industrial R&D laboratories around the world, with viral vectors – such as lentivirus – commonly used to create new cellular models for a wide range of...
The success of hematopoietic stem cell donation is highly dependent on a close match between the donor and recipient human leukocyte antigen (HLA) alleles. DKMS Life Science Lab performs HLA typing of over a million potential donors a year, relying...