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A step closer to simpler liquid biopsy screening

Liquid biopsies offer the potential for the minimally-invasive detection of a growing number of cancers. Epigenomics is using its expertise in epigenetics to develop rapid tests for blood-borne cancer biomarkers, based on the unique DNA methylation fingerprint of cancerous cells.

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Exceptional analytical possibilities from a new cell culture environment

Researchers at the Grenoble Institute of Technology are exploring the potential of biomimetic coatings to aid tissue regeneration. The group has developed an innovative, automated layer-by-layer production technique, allowing high throughput in vitro investigations into the ability of these biomimetic coatings to control stem cell differentiation.

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Timely automation for ultra-sensitive immunodiagnostics

High sensitivity immunoassays allow earlier detection and diagnosis of patient conditions, leading to earlier interventions and better patient prognoses. Immunodiagnostics company Singulex’s unique immunoassay technology allows early detection of even low abundance biomarkers for a wide range of conditions, and the company has partnered with Tecan to develop an intuitive, fully automated platform – the Singulex Clarity® system – which will allow clinical labs to take advantage of this novel technology for routine diagnostics.

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Automation by numbers

Biopharmaceutical production is a complex process compared to small molecule drug manufacture, requiring the interaction of multiple biosynthesis pathways to create the target product. KBI Biopharma is using high throughput bioanalysis to gain an in-depth understanding of these biological processes, ensuring efficient, reproducible and scalable biomanufacturing processes.

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Accessible automation for the novice

High throughput bioprocess development is essential for optimizing run parameters prior to scale-up. University College London’s Advanced Centre for Biochemical Engineering is harnessing the possibilities afforded by automation, using custom-built scripts and programs to make its liquid handling platforms accessible to inexperienced users.

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A natural affinity

Receptor binding assays form an integral part of the preclinical screening service provided by Eurofins Pharma Discovery Services division. The first stage of the protocol is the transfer of tissue samples to a 96-well plate, a process that must be carefully performed to avoid any cross-contamination.

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