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The Blog

Selected category: Mass Spectrometry

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Considering mass spec for therapeutic drug monitoring? Here are 4 pitfalls to avoid

By Dr Manuel Bauer 

As we saw in part 1 of this blog series, liquid chromatography-tandem mass spectrometry (LC-MS/MS) is potentially the new gold standard for therapeutic monitoring of immunosuppressant drugs (ISD). However, for this technology to...

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LC-MS/MS immunosuppressant drug monitoring: from promise to reality

By Manuel Bauer 

Advances in the treatment of disease, such as the many different types of cancer and cardiac diseases, mean that organ and bone marrow transplantation is on the rise.1 This rise has in turn generated an increased need for accurate...

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Six benefits to implementing LC-MS sample prep automation

By Dr Manuel Bauer

Rohit Shroff provides insight from customer success stories on the benefits of automation in the clinical laboratory. Specifically, he answers the question “what can automation do for me” by illustration of the impact that these...

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Automating liquid sample preparation workflow optimizes your clinical LC-MS investment

By Manuel Bauer

So you’ve made the investment in liquid chromatography mass spectrometry (LC-MS) in your clinical/diagnostics laboratory and now you need to get it up and running…adding value to the lab and generating a return. The job will...

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Time to add LC-MS sample prep automation to your clinical/diagnostic testing lab menu

By Manuel Bauer

While MS has been around for over a century, the addition of liquid chromatography-mass spectrometry (LC-MS) in clinical testing laboratories has only become feasible in the last 15 to 20 years. Judith Stone, Senior CLS Specialist,...

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How to boost productivity for LC-MSMS sample prep

By Agnieszka Sitarska

Choosing a method and developing a protocol for small molecule LC-MSMS sample preparation can be a complex process. An effective shortcut is to use an extraction plate built for automation. With fewer processing steps and an...

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ROI from the LC/MS lab: challenges in a regulated environment

By Rohit Schroff

The popularity of mass spectrometry based testing is growing all the time. As a result, businesses in the diagnostics industry offering mass-spectrometry-based clinical assays, especially analytical laboratories in toxicology...

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How to choose a small molecule extraction method and develop a protocol for LC-MSMS sample prep

By Agnieszka Sitarska

In the previous article in this series it became clear that high productivity in small molecule LC-MSMS relies on effective sample prep that supports reproducible results and minimizes downtime for sensitive LC and MS...

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Separation anxiety? Miniaturized parallel chromatography could cure your protein purification woes

By Isabel Patocchi

In the US and EU, there are over 200 approved biotherapeutic drugs already on the market. The rush to evaluate the hundreds of candidates in the pipeline has created a demand for increasingly efficient high throughput technologies...

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Why an Academic Laboratory Does Not Need Automation, and 5 Reasons Why I Disagree

By Rick Luedke You may be convinced that your academic research laboratory is humming along just fine and cannot benefit from, take the time to consider, and perhaps most of all, afford adding automation to your workflow.

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