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Selected category: lab automation

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Solving the top four automation challenges of the discovery lab

By Simon Fogarty

At Tecan, we’ve been solving lab automation problems for over thirty years. In planning for SLAS, I was asked an interesting question: what are the main automation challenges that people face in drug discovery and screening? I can break them down into categories, and illustrate them with the most common requests that we get.

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Everything Your Boss Wants to Know About Liquid Handling

By Bronwen Forster

What does the boss want to achieve by automating a process? The priority is enhanced data quality, followed closely by greater productivity, protecting your investment, and saving time and money. Tecan's Fluent® 780 can meet these critical demands.

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Automating rapid, parallel high throughput screening to accelerate compound optimization

SLAS2017 Presentation by Dr. Bernhard Ellinger, Fraunhofer Institute for Molecular Biology and Applied Ecology, IME, Hamburg, Germany

Fraunhofer IME has had very good success using the Tecan Fluent®  to perform fully automated screening of smaller compound batches rapidly and accurately, in parallel against multiple analytes and with multiple readouts.

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Minimizing Data Variability Caused by Your Microplate Reader

SLAS2017 Presentation by Siegfried Sasshofer, Product Manager, Tecan

The ability to reduce data variability can help greatly increase your confidence in your results. Statistically significant experimental results may not actually be achieved if you review your data and find the margin of error is too high. What do scientists typically do?

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How automated test tube barcoding adds reliability and stops unnecessary errors

By Florence Collins

Scinomix, Inc., founded in 2001, creates customized solutions for labeling tubes, vials and plates in many life science applications. We took the chance to ask Nigel Malterer (CEO) and Jonathan King (Automation Software Engineer) at Scinomix about how automated barcode labeling solutions are helping to improve productivity, reduce errors and costs, and increase control over lab workflows.

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Standardized verification of pipetting performance is key to efficiency and regulatory compliance

By Agnieszka Sitarska

Whatever you are using automated liquid handling for, be it drug development, next generation sequencing, assay development or basic research with cell-based assays, getting correct results is crucial to reaching your goals, quickly and efficiently. And you also need to prove the validity of your data for regulatory compliance. The question is, how can this be achieved with little effort?

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How to make the right choice for barcoding sample tubes – standards, challenges and considerations

By Florence Collins

Barcodes play a central role in minimizing the risk of error in lab automation by providing secure tracking of components throughout the workflow. Barcode-guided lab automation can be simple and cost-effective, with significant paybacks thanks to productivity increases. 

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Tecan delivers sterile tips to your lab bench

By Severin Heynen

As we have learned in previous posts in this series, only pipette tips marked ‘sterile’ are guaranteed with a sterility assurance level (SAL) of 10-6. Pipette tips labeled as ‘Pre-sterile’ do not give such sterility assurances.

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Intelligent robot for colony picking and complete MALDI target preparation

By Kevin Trümpi

Today’s automated microbiological lab uses matrix-assisted laser desorption/ionization (MALDI) for quick, effective and cost saving identification.

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Automated mass spec immunoassay workflow

By Agnieszka Sitarska

The mass spec immunoassay (MSIA) workflow was developed to provide a simple, automated process for purification of targeted analytes for downstream detection using multiple analytical techniques, such as mass spectrometry.

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Automation in the LC-MS lab

By Vince Ahlheit

Vince Ahlheit, Senior Application Scientist, Tecan, provides insight on the benefits of automation in the clinical laboratory.

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Agrigenomics: Tools for plant and animal breeding, fish and fowl

By Enrique Neumann

The term genomics might at first lead you to think of the human genome and the new micro-industry subsectors it has spawned, from prenatal genetic screening for heritable diseases (and one day perhaps to select for "desirable" traits) to companion diagnostics for personalized medicine, and nutraceuticals targeted to correct imbalances in the gut microbiome.Those same types of genomic applications and many, many more can translate directly to the plant and animal world, in which agrigenomic technology is transforming traditional approaches to breeding of commercial species and monitoring and protection of wild populations.

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Six benefits to implementing LC-MS sample prep automation

By Rohit Shroff

Rohit Shroff, Head of Sales Development Tecan provides insight from customer success stories on the benefits of automation in the clinical laboratory. Specifically, he answers the question “what can automation do for me” by illustration of the impact that these solutions have every day ... showing how sample prep automation has overcome workflow bottlenecks in the clinical LC-MS lab with real world tangible results. He shares multiple success stories of labs improving their client services by adopting automation to address the hurdles of productivity, implementation speed, compliance, reproducibility, efficiency, and employee satisfaction and retention.

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11 key points to install and efficiently initiate a new automated assay system in your laboratory

By Hal Wehrenberg

Congratulations. It took you quite some time and effort to convince your management or institution on the value of investing in automating your experimental or clinical workflow. The applications were submitted, the presentations were made and the wheeling and dealing to secure the budget resulted in you and your team landing the investment. You've arrived. Now all you have to do is choose the robot and get it up and running.

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Automating liquid sample preparation workflow optimizes your clinical LC-MS investment

By Rohit Shroff

So you’ve made the investment in liquid chromatography mass spectrometry (LC-MS) in your clinical/diagnostics laboratory and now you need to get it up and running…adding value to the lab and generating a return. The job will certainly include moving from manual to automated sample preparation methods. This can seem an overwhelming task, especially when it involves solid phase extraction (SPE). Sean Orlowicz, Manager, PhenoLogix, offers guidance on a collaborative approach for application support and sample preparation method development.

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Automation, miniaturization, cell based assays and 3D cell culture – the new standards for phenotypic screening

By Simon Fogarty

If you’ve decided you need to incorporate phenotypic screening into your discovery program and you know that one of the new generation of automation platforms is the way forward, what factors should influence your choice?

A Q&A session with Kevin Moore, Manager Liquid Handling Product and Applications Management at Tecan, offers a view of what you should consider.

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How to become fluent in compound management

By Kevin Moore

With years of experience in lab automation, Wolfgang Jörg at Boehringer Ingelheim needed to find a new automation solution for a colleague working with compound management. Presenting at SLAS 2016, Wolfgang said, “We decided to test Fluent® 780. Tecan loaned us the system for free to test for six months providing we agreed to purchase if the system met our expectations.” With its high throughput, flexibility and accuracy, the system exceeded their expectations and has become a critical component in their high throughput compound management solution.

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Automated metabolic analysis in photodynamic tumor therapy

By Siegfried Sasshofer

Photodynamic Therapy (PDT) is being increasingly recognized as having potential for the treatment of tumors, especially dermatological. But using conventional manual methods of recording the metabolic processes that occur as a result of adding the photosensitizer to target cells has major limitations.

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Counting cells is a waste of time

By Siegfried Sasshofer

The hemocytometer has been around for 140 years. It’s an easy, reliable, and trusty tool for all kinds of cell counting applications. It’s beautiful and simple. But measuring the well-being of your cells one click at a time is slow and tedious, and can be near impossible for adherent cells. Shouldn’t you be doing something else with your time?

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Cell counting by the numbers

By Michael Fejtl

“When you can measure what you are speaking about, and express it in numbers, you know something about it.” Lord Kelvin knew that. To be confident in your results, to quickly move your studies forward, and to be the first to publish your conclusions, you need to know that your numbers are right. The proof you need lies in reproducibility, and reproducibility in any cell-based assay starts with accurate cell counts.

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The top 5 pitfalls of custom automation

By Avinash Peddi

What happens when lab automation projects are unsuccessful? One outake is learning that creates a stronger process and methodology. That's exactly what we found at Tecan after working with several hundred customers on lab automation for multiple projects. This presentation from SLAS2016 reveals the top 5 pitfalls of custom automation based on real experience.

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